Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum vs Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide
Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide scores 9.6/9.8 vs Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum at 8.1/9.8. Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide wins for active ingredients.
Head to head

Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum

barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide
Score comparison
Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide takes this one, winning 1 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Peter Thomas Roth WINSIrritation Risk
TIEActive Ingredient Strength
Skinfix WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
26% overlapOnly in Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum
23 unique
Shared ingredients
12 in common
Only in Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide
34 unique
Why Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide comes out ahead
Where Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide really shines is active ingredient strength, scoring 9.2 compared to Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum's 4.3. Its formula features Niacinamide, Lithothamnion Calcareum Extract, and Oligopeptide-2 in high positions, signalling meaningful concentrations.
Hydration Efficacy is another area of separation. Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum scores 9.8 here versus 8.4 for Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide. That difference comes down to how each formula is built — the ingredient list tells the story.
Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide brings Niacinamide, Lithothamnion Calcareum Extract, and Oligopeptide-2 as actives, while peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum relies on Saccharomyces Lysate, Acetyl Hexapeptide-8, and Pentapeptide-18. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
Both sit in the premium bracket, so value comes down to formulation quality. Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide gets the nod here with its 9.6 overall score — you're getting more for a similar outlay.
Our verdict
Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide wins this comparison with a meaningfully stronger ingredient profile and overall score.


Frequently asked questions
Which is better: Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum or Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide?
Based on ingredient analysis, Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide scores higher overall. See the full score breakdown above for details on each attribute.
Do Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum and Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum and Skinfix barrier+ Triple Lipid Activating Serum With Plumping Peptides and Niacinamide?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.