Paula's Choice Clinical Niacinamide 20% Treatment vs Sunday Riley B3 Nice 10% Niacinamide Serum
Paula's Choice Clinical Niacinamide 20% Treatment scores 8.7/9.8 and Sunday Riley B3 Nice 10% Niacinamide Serum scores 8.5/9.8 — a near-tie where your skin type decides the winner.
Head to head

Clinical Niacinamide 20% Treatment

B3 Nice 10% Niacinamide Serum
Score comparison
These two are neck and neck — just 0.2 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Paula's Choice WINSIrritation Risk
TIEActive Ingredient Strength
Sunday Riley WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
9% overlapOnly in Paula's Choice Clinical Niacinamide 20% Treatment
19 unique
Only in Sunday Riley B3 Nice 10% Niacinamide Serum
39 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Active Ingredient Strength is another area of separation. Sunday Riley B3 Nice 10% Niacinamide Serum scores 7.6 here versus 6.7 for Paula's Choice Clinical Niacinamide 20% Treatment. That difference comes down to how each formula is built — the ingredient list tells the story.
Paula's Choice Clinical Niacinamide 20% Treatment brings Niacinamide, Acetyl Glucosamine, and Ascorbyl Glucoside as actives, while sunday Riley B3 Nice 10% Niacinamide Serum relies on Niacinamide, Resveratrol, and Asiaticoside. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Paula's Choice Clinical Niacinamide 20% Treatment is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Anyone who prefers clean, well-vetted formulations
Sunday Riley B3 Nice 10% Niacinamide Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
- Anyone who prefers clean, well-vetted formulations
Value comparison
At mid-range pricing with a score of 8.7, Paula's Choice Clinical Niacinamide 20% Treatment delivers strong value. Sunday Riley B3 Nice 10% Niacinamide Serum sits at the premium level with a 8.5 score — the extra cost doesn't translate to better scores here.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.


Frequently asked questions
Which is better: Paula's Choice Clinical Niacinamide 20% Treatment or Sunday Riley B3 Nice 10% Niacinamide Serum?
Based on ingredient analysis, Paula's Choice Clinical Niacinamide 20% Treatment scores higher overall. See the full score breakdown above for details on each attribute.
Do Paula's Choice Clinical Niacinamide 20% Treatment and Sunday Riley B3 Nice 10% Niacinamide Serum share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Paula's Choice Clinical Niacinamide 20% Treatment and Sunday Riley B3 Nice 10% Niacinamide Serum?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.