Madecassoside
Also known as: Madecassoside
Madecassoside is an active ingredient — centella derivative for calming skin. It's found in 131 products in our database, making it one of the most common ingredients.
What it does
Centella derivative for calming skin
Madecassoside is one of the four key triterpenoid saponins found in Centella asiatica. When isolated and used at precise concentrations, it delivers the plant's most-studied benefits without the variability of whole-extract formulations. In clinical studies, madecassoside has been shown to inhibit pro-inflammatory cytokines, stimulate collagen synthesis, and accelerate wound healing. At 0.1–0.5% it is commonly used in redness-reduction and post-procedure creams; at lower doses it appears in calming toners, essences, and barrier creams across the K-beauty derma-cosmetic range. Pair madecassoside with niacinamide for a comprehensive barrier-and-tone routine, or with retinol to offset irritation. It is one of the safest actives in skincare — suitable for pregnancy, sensitive skin, and daily use year-round.
Who it's best for
People with specific skin concerns looking for targeted treatment.
- Those dealing with acne, hyperpigmentation, fine lines, or uneven texture
- Anyone ready to build an active-focused routine (start slowly)
- Skin that has already adapted to a basic hydration routine
Works well with
- +Draws in moisture(humectant)
- +Softens and smooths(emollient)
- +UV protection(sunscreen)
Use caution with
- !Works on your skin(active)Layering multiple actives can increase irritation — introduce one at a time and monitor your skin's response.
131 products
Works on your skin
Best products with Madecassoside
Toners
See all toners→Serums
See all serums→exfoliant
See all exfoliant→Moisturisers
See all moisturisers→SPF products
See all spf products→Masks
See all masks→Top products with Madecassoside
BALANCEFUL 5D Cica Complex AHA Pore Refining Toner for Clear, Smooth Skin
Reset to Balance Mode Kit - Routine Set for Oily Skin and Pore + Shine Control
A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
DIVE IN 5D Hyaluronic Acid Ultra Hydrating Serum for Plump & Glow Skin
Balance Mode Pore Polishing Peel-Off Face Mask with Salicylic Acid to Control Shine & Smooth Texture
Mini Vitamin C Rapid Brightening Gift Set for Dark Spots
BALANCEFUL 5D Cica Complex Soothing Cream for Sensitive & Redness Skin
DIVE IN Hydration Starter Set
Cicapair ™ Tiger Grass Camo Drops Color Corrector SPF 35
Volcanic Swirl Exfoliating Pore Mask
BALANCEFUL 5D Cica Complex Redness Reducing Serum for Calming & Hydration
PDRN Reedle Shot Firming Eye Cream
Mini Mami Wata Barrier Strengthening Face Mist with Cica, Panthenol, Ectoin for Sensitive, Irritated Skin
Balance Mode Shine Control & Pore-Minimizing Lightweight Moisturizer for Oily Skin
BALANCEFUL 5D Cica Complex Cleansing Gel for Sensitive Skin & Gentle Makeup Removal
Cica Daily Soothing Mask Sheet
DIVE IN 5D Hyaluronic Acid Intensive Cream for dry Skin & Moisture Barrier Support
Retinol Cica Ampoule
Rapid Vitamin C Brightening Serum for Dark Spots + Post-Breakout Marks
B3 Nice 10% Niacinamide Serum
Frequently asked questions
What does Madecassoside do in skincare?
Centella derivative for calming skin
Is Madecassoside safe for sensitive skin?
Madecassoside is generally well-tolerated and has no specific concern flags in our database. As with any ingredient, patch-test if you have highly reactive skin.
What products contain Madecassoside?
131 products in our database contain Madecassoside. The highest-rated is Torriden BALANCEFUL 5D Cica Complex AHA Pore Refining Toner for Clear, Smooth Skin scoring 9.6/9.8.
Can I use Madecassoside every day?
Many actives are best introduced gradually — start with 2-3 times per week and increase as your skin adapts. Strong actives like retinoids are often best used at night.