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Paula's Choice Clinical 1% Retinol Treatment scores 8.9/9.8 vs Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum at 8.3/9.8. Paula's Choice Clinical 1% Retinol Treatment wins for active ingredients.
Paula's Choice Clinical 1% Retinol Treatment edges ahead, winning 2 of 5 attributes.
Scores last verified: June 2026
37 unique
10 in common
21 unique
Where Paula's Choice Clinical 1% Retinol Treatment really shines is active ingredient strength, scoring 7.1 compared to Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum's 4.3. Its formula features Retinol, Tetrahexyldecyl Ascorbate, and Palmitoyl Oligopeptide in high positions, signalling meaningful concentrations.
Ingredient Transparency is another area of separation. Paula's Choice Clinical 1% Retinol Treatment scores 8.8 here versus 8.5 for Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum. That difference comes down to how each formula is built — the ingredient list tells the story.
Paula's Choice Clinical 1% Retinol Treatment brings Retinol, Tetrahexyldecyl Ascorbate, and Palmitoyl Oligopeptide as actives, while peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum relies on Saccharomyces Lysate, Acetyl Hexapeptide-8, and Pentapeptide-18. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Paula's Choice Clinical 1% Retinol Treatment is better if you have
Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum is better if you have
At mid-range pricing with a score of 8.9, Paula's Choice Clinical 1% Retinol Treatment delivers strong value. Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum sits at the premium level with a 8.3 score — the extra cost doesn't translate to better scores here.
Paula's Choice Clinical 1% Retinol Treatment edges ahead with a slightly stronger formulation, but Peter Thomas Roth Peptide Skinjection™ Amplified Wrinkle-Fix Refillable Serum is still a solid pick.
Based on ingredient analysis, Paula's Choice Clinical 1% Retinol Treatment scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.