innisfree Retinol Cica Ampoule vs medicube Hyaluronic Multi Peptide PDRN Serum
medicube Hyaluronic Multi Peptide PDRN Serum scores 8.8/9.8 vs innisfree Retinol Cica Ampoule at 8.5/9.8. medicube Hyaluronic Multi Peptide PDRN Serum wins for active ingredients.
Head to head
Retinol Cica Ampoule
Hyaluronic Multi Peptide PDRN Serum
Score comparison
medicube Hyaluronic Multi Peptide PDRN Serum edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
medicube WINSIrritation Risk
TIEActive Ingredient Strength
medicube WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
33% overlapOnly in innisfree Retinol Cica Ampoule
11 unique
Shared ingredients
13 in common
Only in medicube Hyaluronic Multi Peptide PDRN Serum
27 unique
Why medicube Hyaluronic Multi Peptide PDRN Serum comes out ahead
Where medicube Hyaluronic Multi Peptide PDRN Serum really shines is active ingredient strength, scoring 7.5 compared to innisfree Retinol Cica Ampoule's 6.4. Its formula features Niacinamide, Allantoin, and Adenosine in high positions, signalling meaningful concentrations.
Hydration Efficacy is another area of separation. medicube Hyaluronic Multi Peptide PDRN Serum scores 9.8 here versus 9.2 for innisfree Retinol Cica Ampoule. That difference comes down to how each formula is built — the ingredient list tells the story.
medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while innisfree Retinol Cica Ampoule relies on Niacinamide, Tocopherol, and Retinol. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
innisfree Retinol Cica Ampoule is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
innisfree Retinol Cica Ampoule comes in at budget pricing with a 8.5 score, which is solid value at that tier.
Our verdict
medicube Hyaluronic Multi Peptide PDRN Serum edges ahead with a slightly stronger formulation, but innisfree Retinol Cica Ampoule is still a solid pick.
Frequently asked questions
Which is better: innisfree Retinol Cica Ampoule or medicube Hyaluronic Multi Peptide PDRN Serum?
Based on ingredient analysis, medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.
Do innisfree Retinol Cica Ampoule and medicube Hyaluronic Multi Peptide PDRN Serum share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between innisfree Retinol Cica Ampoule and medicube Hyaluronic Multi Peptide PDRN Serum?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.