Copper Amino Isolate Serum 3 1:1 (CAIS3)
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NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) scores 7.7/9.8 overall. It ranks highest in low irritation risk (9.5) and formulation safety (9.0).
✶ Hero ingredients
One of the most effective humectants
Works on your skin
Works on your skin
Score breakdown
Estimated — based on ingredient analysis. Scores refine as user reviews are added.
Scores last verified: July 2026
What makes NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) stand out
NIOD Copper Amino Isolate Serum 3 1:1 (CAIS3) is a solid serum with an overall score of 7.7/9.8. it delivers a well-rounded formulation that balances efficacy with gentleness. The formula leads with Glycerin, Tripeptide-29, Tripeptide-1 Copper Acetate — ingredients that support the skin barrier and moisture levels.
It performs well on low irritation risk (9.5) and active strength (7.7). On the flip side, hydration could be stronger.
Is this right for you?
Great for
- ✓Sensitive skin — low irritation risk with a gentle formulation
- ✓Anyone wanting visible results — solid active ingredient lineup
- ✓Safety-conscious shoppers — clean formulation with minimal flags
May not suit
- ⚠Very dry skin types looking for heavy-duty moisture
Key ingredients
- ✶Glycerin
Draws in moisture — #2 in the INCI list
- ✶Tripeptide-29
Works on your skin — #3 in the INCI list
- ✶Tripeptide-1 Copper Acetate
Works on your skin — #4 in the INCI list
- ✶Tripeptide-1 Acetate
Works on your skin — #5 in the INCI list
- ✶Myristoyl Nonapeptide-3
Works on your skin — #6 in the INCI list
What creators are saying
TikTokFull ingredient list
21 ingredients — listed in INCI order (highest concentration first)
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Ingredient breakdown
- Draws in moisture6
- Works on your skin6
- Keeps the product fresh5
- Holds the formula together3
- Other ingredient1