Biome-Balancing Clear & Prevent Acne Treatment Serum
Murad Biome-Balancing Clear & Prevent Acne Treatment Serum scores 8.1/9.8 overall. It ranks highest in hydration efficacy (9.7) and low irritation risk (9.5).
✶ Hero ingredients
Acid compound
Draws in moisture
Gentle AHA suitable for sensitive skin
Score breakdown
Scores last verified: July 2026
What makes Murad Biome-Balancing Clear & Prevent Acne Treatment Serum stand out
Murad Biome-Balancing Clear & Prevent Acne Treatment Serum is an excellent serum with an overall score of 8.1/9.8. Positioned in the premium bracket, it delivers a well-rounded formulation that balances efficacy with gentleness. The formula leads with Propanediol, Mandelic Acid, Glycerin — ingredients that support the skin barrier and moisture levels.
It performs well on hydration (9.7) and low irritation risk (9.5). On the flip side, active ingredient concentration is on the lighter side.
Is this right for you?
Great for
- ✓Dry or dehydrated skin — strong moisture-binding profile
- ✓Sensitive skin — low irritation risk with a gentle formulation
- ✓Safety-conscious shoppers — clean formulation with minimal flags
May not suit
- ⚠Those seeking potent actives — this leans more maintenance than treatment
Key ingredients
- ✶Propanediol
Draws in moisture — #3 in the INCI list
- ✶Mandelic Acid
Works on your skin — #4 in the INCI list
- ✶Glycerin
Draws in moisture — #5 in the INCI list
- ✶Erythritol
Draws in moisture — #6 in the INCI list
- ✶Pentylene Glycol
Draws in moisture — #7 in the INCI list
What creators are saying
TikTokTikTok reviewers love that this serum clears breakouts while supporting your skin's microbiome to prevent them from returning, with users noting their skin feels more balanced, less irritated, and visibly clearer. They appreciate that it works without irritation by feeding good bacteria and combining salicylic, mandelic, and glutamic acids to smooth and calm the skin. The product is recommended for anyone with acne-prone skin, including those dealing with hormonal or recurring breakouts who want a gentler approach than traditional acne treatments.
Based on 5 creator reviewsFull ingredient list
37 ingredients — listed in INCI order (highest concentration first)
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Ingredient breakdown
- Works on your skin11
- Draws in moisture10
- Formula balancers6
- Keeps the product fresh4
- Other ingredient3
- Softens and smooths2
- Holds the formula together1