Azelaic Acid 16 Calming Serum
medicube Azelaic Acid 16 Calming Serum scores 7.7/9.8 overall. It ranks highest in low irritation risk (9.3) and formulation safety (9.0).
✶ Hero ingredients
Reduces redness and evens skin tone
Lightweight humectant and solvent
Draws in moisture
Score breakdown
Estimated — based on ingredient analysis. Scores refine as user reviews are added.
Scores last verified: July 2026
What makes medicube Azelaic Acid 16 Calming Serum stand out
medicube Azelaic Acid 16 Calming Serum is a solid serum with an overall score of 7.7/9.8. it delivers a well-rounded formulation that balances efficacy with gentleness. The formula leads with Azelaic Acid, Butylene Glycol, Propanediol — ingredients that actively target skin concerns.
It performs well on low irritation risk (9.3).
Is this right for you?
Great for
- ✓Sensitive skin — low irritation risk with a gentle formulation
- ✓Safety-conscious shoppers — clean formulation with minimal flags
- ✓Ingredient-aware buyers — transparent, well-documented formula
Key ingredients
- ✶Azelaic Acid
Works on your skin — #2 in the INCI list
- ✶Butylene Glycol
Draws in moisture — #3 in the INCI list
- ✶Propanediol
Draws in moisture — #4 in the INCI list
- ✶Propylene Glycol
Draws in moisture — #6 in the INCI list
- ✶Niacinamide
Works on your skin — #8 in the INCI list
What creators are saying
TikTokReviewers love that this serum is effective for acne-prone skin thanks to its strong 16% azelaic acid concentration, making it a solid choice if you're dealing with breakouts. The main drawback is that it contains alcohol dehydrated, which some people find irritating, and it rates as a good but not top-tier option compared to other azelaic acid serums on the market. It's best suited for those with resilient, acne-prone skin who can tolerate higher concentrations and alcohol in their formulas.
Based on 3 creator reviewsFull ingredient list
28 ingredients — listed in INCI order (highest concentration first)
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Ingredient breakdown
- Works on your skin10
- Softens and smooths5
- Draws in moisture4
- Other ingredient3
- Formula balancers2
- Keeps the product fresh2
- Added scent1
- Holds the formula together1