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Paula's Choice Clinical 1% Retinol Treatment scores 8.9/9.8 vs SK-II R.N.A. Power Airy Milky Lotion at 8.0/9.8. Paula's Choice Clinical 1% Retinol Treatment wins for active ingredients.
Paula's Choice Clinical 1% Retinol Treatment edges ahead, winning 2 of 5 attributes.
Scores last verified: April 2026
36 unique
11 in common
12 unique
Where Paula's Choice Clinical 1% Retinol Treatment really shines is active ingredient strength, scoring 7.1 compared to SK-II R.N.A. Power Airy Milky Lotion's 4.2. Its formula features Retinol, Palmitoyl Tetrapeptide-7, and Dipotassium Glycyrrhizate in high positions, signalling meaningful concentrations.
Hydration Efficacy is another area of separation. Paula's Choice Clinical 1% Retinol Treatment scores 9.8 here versus 8.3 for SK-II R.N.A. Power Airy Milky Lotion. That difference comes down to how each formula is built — the ingredient list tells the story.
Paula's Choice Clinical 1% Retinol Treatment brings Retinol, Palmitoyl Tetrapeptide-7, and Dipotassium Glycyrrhizate as actives, while sK-II R.N.A. Power Airy Milky Lotion relies on Niacinamide, Adenosine, and Tocopheryl Acetate. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Paula's Choice Clinical 1% Retinol Treatment is better if you have
SK-II R.N.A. Power Airy Milky Lotion is better if you have
At mid-range pricing with a score of 8.9, Paula's Choice Clinical 1% Retinol Treatment delivers strong value. SK-II R.N.A. Power Airy Milky Lotion sits at the luxury level with a 8.0 score — the extra cost doesn't translate to better scores here.
Paula's Choice Clinical 1% Retinol Treatment edges ahead with a slightly stronger formulation, but SK-II R.N.A. Power Airy Milky Lotion is still a solid pick.
Based on ingredient analysis, Paula's Choice Clinical 1% Retinol Treatment scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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