Murad Retinol Youth Renewal Serum vs SK-II R.N.A. Power Anti-Aging Cream
Murad Retinol Youth Renewal Serum scores 8.4/9.8 vs SK-II R.N.A. Power Anti-Aging Cream at 8.1/9.8. Murad Retinol Youth Renewal Serum wins for active ingredients.
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Murad Retinol Youth Renewal Serum scores 8.4/9.8 vs SK-II R.N.A. Power Anti-Aging Cream at 8.1/9.8. Murad Retinol Youth Renewal Serum wins for active ingredients.

Murad Retinol Youth Renewal Serum edges ahead, winning 3 of 5 attributes.
Scores last verified: April 2026
40 unique
9 in common
Where Murad Retinol Youth Renewal Serum really shines is active ingredient strength, scoring 5.1 compared to SK-II R.N.A. Power Anti-Aging Cream's 4.1. Its formula features Retinol, Ceramide Np, and Solanum Lycopersicum (Tomato) Fruit Extract in high positions, signalling meaningful concentrations.
Formulation Safety is another area of separation. Murad Retinol Youth Renewal Serum scores 8.5 here versus 8.0 for SK-II R.N.A. Power Anti-Aging Cream. That difference comes down to how each formula is built — the ingredient list tells the story.
Murad Retinol Youth Renewal Serum brings Retinol, Ceramide Np, and Solanum Lycopersicum (Tomato) Fruit Extract as actives, while sK-II R.N.A. Power Anti-Aging Cream relies on Niacinamide, Tocopheryl Acetate, and Chlorella Vulgaris Extract. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Murad Retinol Youth Renewal Serum is better if you have
SK-II R.N.A. Power Anti-Aging Cream is better if you have
At premium pricing with a score of 8.4, Murad Retinol Youth Renewal Serum delivers strong value. SK-II R.N.A. Power Anti-Aging Cream sits at the luxury level with a 8.1 score — the extra cost doesn't translate to better scores here.
Murad Retinol Youth Renewal Serum edges ahead with a slightly stronger formulation, but SK-II R.N.A. Power Anti-Aging Cream is still a solid pick.

Based on ingredient analysis, Murad Retinol Youth Renewal Serum scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.