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Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol scores 8.2/9.8 and SK-II R.N.A. Power Anti-Aging Cream scores 8.4/9.8 — a near-tie where your skin type decides the winner.
These two are neck and neck — just 0.2 points apart.
Scores last verified: June 2026
25 unique
These two moisturisers take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Formulation Safety is another area of separation. Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol scores 9.0 here versus 8.0 for SK-II R.N.A. Power Anti-Aging Cream. That difference comes down to how each formula is built — the ingredient list tells the story.
SK-II R.N.A. Power Anti-Aging Cream brings Galactomyces Ferment Filtrate, Niacinamide, and Tocopheryl Acetate as actives, while mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol relies on Retinol, Tocopherol, and Ceramide Np. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol is better if you have
SK-II R.N.A. Power Anti-Aging Cream is better if you have
Both sit in the luxury bracket, so value comes down to formulation quality. SK-II R.N.A. Power Anti-Aging Cream gets the nod here with its 8.4 overall score — you're getting more for a similar outlay.
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.
Based on ingredient analysis, SK-II R.N.A. Power Anti-Aging Cream scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.