medicube Hyaluronic Multi Peptide PDRN Serum vs Sulwhasoo Overnight Vitalizing Mask
medicube Hyaluronic Multi Peptide PDRN Serum scores 8.8/9.8 and Sulwhasoo Overnight Vitalizing Mask scores 9.0/9.8 — a near-tie where your skin type decides the winner.
Head to head

Hyaluronic Multi Peptide PDRN Serum
Overnight Vitalizing Mask
Score comparison
These two are neck and neck — just 0.2 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
TIEIrritation Risk
TIEActive Ingredient Strength
medicube WINSIngredient Transparency
TIEFormulation Safety
medicube WINSIngredient face-off
17% overlapOnly in medicube Hyaluronic Multi Peptide PDRN Serum
31 unique
Shared ingredients
9 in common
Only in Sulwhasoo Overnight Vitalizing Mask
43 unique
Why these two are neck and neck
These two masks take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Formulation Safety is another area of separation. medicube Hyaluronic Multi Peptide PDRN Serum scores 9.0 here versus 8.0 for Sulwhasoo Overnight Vitalizing Mask. That difference comes down to how each formula is built — the ingredient list tells the story.
Sulwhasoo Overnight Vitalizing Mask brings Camellia Sinensis Leaf Extract, Panax Ginseng Root Extract, and Ophiopogon Japonicus Root Extract as actives, while medicube Hyaluronic Multi Peptide PDRN Serum relies on Niacinamide, Allantoin, and Adenosine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Sulwhasoo Overnight Vitalizing Mask is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
Value comparison
Sulwhasoo Overnight Vitalizing Mask comes in at luxury pricing with a 9.0 score, which is solid value at that tier.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.

Frequently asked questions
Which is better: medicube Hyaluronic Multi Peptide PDRN Serum or Sulwhasoo Overnight Vitalizing Mask?
Based on ingredient analysis, Sulwhasoo Overnight Vitalizing Mask scores higher overall. See the full score breakdown above for details on each attribute.
Do medicube Hyaluronic Multi Peptide PDRN Serum and Sulwhasoo Overnight Vitalizing Mask share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between medicube Hyaluronic Multi Peptide PDRN Serum and Sulwhasoo Overnight Vitalizing Mask?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.