medicube Hyaluronic Multi Peptide PDRN Serum vs medicube Zero Pore Pad 2.0
medicube Hyaluronic Multi Peptide PDRN Serum scores 8.8/9.8 vs medicube Zero Pore Pad 2.0 at 8.4/9.8. medicube Hyaluronic Multi Peptide PDRN Serum wins for hydration.
Head to head

Hyaluronic Multi Peptide PDRN Serum
Zero Pore Pad 2.0
Score comparison
medicube Hyaluronic Multi Peptide PDRN Serum edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
medicube WINSIrritation Risk
TIEActive Ingredient Strength
medicube WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
30% overlapOnly in medicube Hyaluronic Multi Peptide PDRN Serum
28 unique
Shared ingredients
12 in common
Only in medicube Zero Pore Pad 2.0
19 unique
Why medicube Hyaluronic Multi Peptide PDRN Serum comes out ahead
Where medicube Hyaluronic Multi Peptide PDRN Serum really shines is hydration efficacy, scoring 9.8 compared to medicube Zero Pore Pad 2.0's 7.4. With Propanediol, Glycerin, and Trehalose in its top ingredients, medicube Hyaluronic Multi Peptide PDRN Serum delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. medicube Hyaluronic Multi Peptide PDRN Serum scores 7.5 here versus 6.3 for medicube Zero Pore Pad 2.0. That difference comes down to how each formula is built — the ingredient list tells the story.
medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while medicube Zero Pore Pad 2.0 relies on Niacinamide, Allantoin, and Gluconolactone. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
medicube Zero Pore Pad 2.0 is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
Value comparison
medicube Zero Pore Pad 2.0 comes in at mid-range pricing with a 8.4 score, which is solid value at that tier.
Our verdict
medicube Hyaluronic Multi Peptide PDRN Serum edges ahead with a slightly stronger formulation, but medicube Zero Pore Pad 2.0 is still a solid pick.

Frequently asked questions
Which is better: medicube Hyaluronic Multi Peptide PDRN Serum or medicube Zero Pore Pad 2.0?
Based on ingredient analysis, medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.
Do medicube Hyaluronic Multi Peptide PDRN Serum and medicube Zero Pore Pad 2.0 share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between medicube Hyaluronic Multi Peptide PDRN Serum and medicube Zero Pore Pad 2.0?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.