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Medicube Deep Vita A… vs SK-II R.N.A. Power A… — Which Is Better? | Gracie

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Medicube Deep Vita A Retinol Serum vs SK-II R.N.A. Power Airy Milky Lotion

Medicube Deep Vita A Retinol Serum scores 8.9/9.8 vs SK-II R.N.A. Power Airy Milky Lotion at 8.0/9.8. Medicube Deep Vita A Retinol Serum wins for active ingredients.

Head to head

Medicube

Deep Vita A Retinol Serum

serum

8.9

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Ingredients

Niacinamide
Retinol
Hyaluronic Acid
Salicylic Acid

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Honest skincare intel. No jargon, no gatekeeping — just the ingredients decoded.

SK-II

R.N.A. Power Airy Milky Lotion

moisturiserluxury

8.0

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Score comparison

Medicube Deep Vita A Retinol Serum edges ahead, winning 2 of 5 attributes.

Medicube wins 2

Tied 3

SK-II wins 0

8.9Medicube

+0.9vs

8.0SK-II

Scores last verified: April 2026

Attribute battle

Hydration Efficacy

Medicube WINS

9.8

8.3

Medicube

SK-II

Irritation Risk

TIE

9.5

Medicube

SK-II

Active Ingredient Strength

Medicube WINS

6.7

4.2

Medicube

SK-II

Ingredient Transparency

TIE

8.8

Medicube

SK-II

Formulation Safety

TIE

9.0

Medicube

SK-II

Ingredient face-off

15% overlap

53Medicube

8Shared

23SK-II

Only in Medicube Deep Vita A Retinol Serum

45 unique

Dipropylene Glycol Propanediol 2-Hexanediol Coco-Caprylate/Caprate Squalane Polyglyceryl-3 Distearate Dimethyl Isosorbide Pentylene Glycol Hydrogenated Lecithin Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer+35 more

Shared ingredients

8 in common

Water Butylene Glycol Glycerin Niacinamide Panthenol Adenosine Sodium Hyaluronate Disodium Edta

Only in SK-II R.N.A. Power Airy Milky Lotion

15 unique

Isododecane Dimethicone Polysilicone-11 Hydrogenated Polydecene Trehalose Inositol Glyceryl Stearate Peg-100 Stearate Cetearyl Alcohol Behenyl Alcohol+5 more

Why Medicube Deep Vita A Retinol Serum comes out ahead

Where Medicube Deep Vita A Retinol Serum really shines is active ingredient strength, scoring 6.7 compared to SK-II R.N.A. Power Airy Milky Lotion's 4.2. Its formula features Niacinamide, Allantoin, and Dipotassium Glycyrrhizate in high positions, signalling meaningful concentrations.

Hydration Efficacy is another area of separation. Medicube Deep Vita A Retinol Serum scores 9.8 here versus 8.3 for SK-II R.N.A. Power Airy Milky Lotion. That difference comes down to how each formula is built — the ingredient list tells the story.

Medicube Deep Vita A Retinol Serum brings Niacinamide, Allantoin, and Dipotassium Glycyrrhizate as actives, while sK-II R.N.A. Power Airy Milky Lotion relies on Niacinamide, Adenosine, and Tocopheryl Acetate. Both approaches have merit, but the positioning and supporting ingredients make the difference.

Best for your skin type

Medicube Deep Vita A Retinol Serum is better if you have

Sensitive skin — the low-irritation formula keeps things gentle
Dry or dehydrated skin that craves moisture, thanks to Dipropylene Glycol
Anyone who prefers clean, well-vetted formulations

SK-II R.N.A. Power Airy Milky Lotion is better if you have

Sensitive skin — the low-irritation formula keeps things gentle
Dry or dehydrated skin that craves moisture, thanks to Glycerin
Anyone who prefers clean, well-vetted formulations

Value comparison

SK-II R.N.A. Power Airy Milky Lotion comes in at luxury pricing with a 8.0 score, which is solid value at that tier.

Our verdict

✶ Our verdict

+0.9 lead

Medicube Deep Vita A Retinol Serum edges ahead with a slightly stronger formulation, but SK-II R.N.A. Power Airy Milky Lotion is still a solid pick.

8.9Medicube

8.0SK-II

Frequently asked questions

Which is better: Medicube Deep Vita A Retinol Serum or SK-II R.N.A. Power Airy Milky Lotion?

Based on ingredient analysis, Medicube Deep Vita A Retinol Serum scores higher overall. See the full score breakdown above for details on each attribute.

Do Medicube Deep Vita A Retinol Serum and SK-II R.N.A. Power Airy Milky Lotion share ingredients?

Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.

What's the main difference between Medicube Deep Vita A Retinol Serum and SK-II R.N.A. Power Airy Milky Lotion?

The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.

Full analysis: Medicube Deep Vita A Retinol Serum→Full analysis: SK-II R.N.A. Power Airy Milky Lotion→

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