medicube Deep Vita A Retinol Serum vs medicube Hyaluronic Multi Peptide PDRN Serum
medicube Deep Vita A Retinol Serum scores 8.6/9.8 and medicube Hyaluronic Multi Peptide PDRN Serum scores 8.8/9.8 — a near-tie where your skin type decides the winner.
Head to head

Deep Vita A Retinol Serum

Hyaluronic Multi Peptide PDRN Serum
Score comparison
These two are neck and neck — just 0.2 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
TIEIrritation Risk
TIEActive Ingredient Strength
medicube WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
26% overlapOnly in medicube Deep Vita A Retinol Serum
39 unique
Shared ingredients
14 in common
Only in medicube Hyaluronic Multi Peptide PDRN Serum
26 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while medicube Deep Vita A Retinol Serum relies on Niacinamide, Allantoin, and Dipotassium Glycyrrhizate. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
medicube Deep Vita A Retinol Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Dipropylene Glycol
- Anyone who prefers clean, well-vetted formulations
medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.


Frequently asked questions
Which is better: medicube Deep Vita A Retinol Serum or medicube Hyaluronic Multi Peptide PDRN Serum?
Based on ingredient analysis, medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.
Do medicube Deep Vita A Retinol Serum and medicube Hyaluronic Multi Peptide PDRN Serum share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between medicube Deep Vita A Retinol Serum and medicube Hyaluronic Multi Peptide PDRN Serum?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.