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Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 8.9/9.8 vs SK-II R.N.A. Power Anti-Aging Cream at 8.4/9.8. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide wins for active ingredients.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead, winning 3 of 5 attributes.
Scores last verified: June 2026
29 unique
10 in common
33 unique
Where Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide really shines is active ingredient strength, scoring 7.7 compared to SK-II R.N.A. Power Anti-Aging Cream's 5.7. Its formula features Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine in high positions, signalling meaningful concentrations.
Formulation Safety is another area of separation. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.0 here versus 8.0 for SK-II R.N.A. Power Anti-Aging Cream. That difference comes down to how each formula is built — the ingredient list tells the story.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while sK-II R.N.A. Power Anti-Aging Cream relies on Galactomyces Ferment Filtrate, Niacinamide, and Tocopheryl Acetate. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
SK-II R.N.A. Power Anti-Aging Cream is better if you have
At premium pricing with a score of 8.9, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers strong value. SK-II R.N.A. Power Anti-Aging Cream sits at the luxury level with a 8.4 score — the extra cost doesn't translate to better scores here.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead with a slightly stronger formulation, but SK-II R.N.A. Power Anti-Aging Cream is still a solid pick.
Based on ingredient analysis, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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