Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide vs Naturium Multi-Peptide Moisturizer
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.3/9.8 vs Naturium Multi-Peptide Moisturizer at 8.5/9.8. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide wins for active ingredients.
Head to head

Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
Multi-Peptide Moisturizer
Score comparison
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Kiehl's Since 1851 WINSIrritation Risk
TIEActive Ingredient Strength
Naturium WINSIngredient Transparency
Naturium WINSFormulation Safety
TIEIngredient face-off
25% overlapOnly in Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
28 unique
Shared ingredients
11 in common
Only in Naturium Multi-Peptide Moisturizer
33 unique
Why Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide comes out ahead
Where Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide really shines is active ingredient strength, scoring 7.7 compared to Naturium Multi-Peptide Moisturizer's 8.3. Its formula features Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine in high positions, signalling meaningful concentrations.
Hydration Efficacy is another area of separation. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.4 here versus 8.9 for Naturium Multi-Peptide Moisturizer. That difference comes down to how each formula is built — the ingredient list tells the story.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while naturium Multi-Peptide Moisturizer relies on Niacinamide, Palmitoyl Tripeptide-5, and Palmitoyl Tripeptide-1. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Naturium Multi-Peptide Moisturizer is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
At premium pricing with a score of 9.3, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers strong value. Naturium Multi-Peptide Moisturizer sits at the budget level with a 8.5 score — the extra cost doesn't translate to better scores here.
Our verdict
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead with a slightly stronger formulation, but Naturium Multi-Peptide Moisturizer is still a solid pick.

Frequently asked questions
Which is better: Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide or Naturium Multi-Peptide Moisturizer?
Based on ingredient analysis, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores higher overall. See the full score breakdown above for details on each attribute.
Do Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide and Naturium Multi-Peptide Moisturizer share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide and Naturium Multi-Peptide Moisturizer?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.