Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide vs medicube Zero Pore Pad 2.0
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.3/9.8 vs medicube Zero Pore Pad 2.0 at 8.4/9.8. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide wins for hydration.
Head to head

Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
Zero Pore Pad 2.0
Score comparison
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Kiehl's Since 1851 WINSIrritation Risk
TIEActive Ingredient Strength
Kiehl's Since 1851 WINSIngredient Transparency
medicube WINSFormulation Safety
TIEIngredient face-off
10% overlapOnly in Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
35 unique
Only in medicube Zero Pore Pad 2.0
27 unique
Why Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide comes out ahead
Where Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide really shines is hydration efficacy, scoring 9.4 compared to medicube Zero Pore Pad 2.0's 7.4. With Glycerin, Butylene Glycol, and Pentylene Glycol in its top ingredients, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 7.7 here versus 6.3 for medicube Zero Pore Pad 2.0. That difference comes down to how each formula is built — the ingredient list tells the story.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while medicube Zero Pore Pad 2.0 relies on Niacinamide, Allantoin, and Gluconolactone. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
medicube Zero Pore Pad 2.0 is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
Value comparison
At premium pricing with a score of 9.3, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers strong value. medicube Zero Pore Pad 2.0 sits at the mid-range level with a 8.4 score — the extra cost doesn't translate to better scores here.
Our verdict
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead with a slightly stronger formulation, but medicube Zero Pore Pad 2.0 is still a solid pick.

Frequently asked questions
Which is better: Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide or medicube Zero Pore Pad 2.0?
Based on ingredient analysis, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores higher overall. See the full score breakdown above for details on each attribute.
Do Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide and medicube Zero Pore Pad 2.0 share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide and medicube Zero Pore Pad 2.0?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.