Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum vs Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.3/9.8 vs Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum at 8.9/9.8. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide wins for hydration.
Head to head
Retinol Skin-Renewing Daily Micro-Dose Serum

Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
Score comparison
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead, winning 0 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
TIEIrritation Risk
TIEActive Ingredient Strength
TIEIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
90% overlapOnly in Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum
4 unique
Shared ingredients
38 in common
Only in Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
1 unique
Why Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide comes out ahead
Where Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide really shines is hydration efficacy, scoring 9.4 compared to Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum's 9.6. With Glycerin, Butylene Glycol, and Pentylene Glycol in its top ingredients, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers stronger moisture-binding capability.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum relies on Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
Both sit in the premium bracket, so value comes down to formulation quality. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide gets the nod here with its 9.3 overall score — you're getting more for a similar outlay.
Our verdict
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead with a slightly stronger formulation, but Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum is still a solid pick.

Frequently asked questions
Which is better: Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum or Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide?
Based on ingredient analysis, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores higher overall. See the full score breakdown above for details on each attribute.
Do Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum and Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum and Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.