Drunk Elephant The Littles 8.0 vs IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles
Drunk Elephant The Littles 8.0 scores 9.8/9.8 vs IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles at 9.0/9.8. Drunk Elephant The Littles 8.0 wins for active ingredients.
Head to head

The Littles 8.0

Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles
Score comparison
Drunk Elephant The Littles 8.0 edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
TIEIrritation Risk
TIEActive Ingredient Strength
Drunk Elephant WINSIngredient Transparency
Drunk Elephant WINSFormulation Safety
TIEIngredient face-off
10% overlapOnly in Drunk Elephant The Littles 8.0
113 unique
Shared ingredients
12 in common
Only in IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles
23 unique
Why Drunk Elephant The Littles 8.0 comes out ahead
Where Drunk Elephant The Littles 8.0 really shines is active ingredient strength, scoring 9.8 compared to IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles's 4.7. Its formula features Cucumis Melo Cantalupensis Fruit Extract, Dipotassium Glycyrrhizate, and Tocopherol in high positions, signalling meaningful concentrations.
Ingredient Transparency is another area of separation. Drunk Elephant The Littles 8.0 scores 8.8 here versus 8.5 for IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles. That difference comes down to how each formula is built — the ingredient list tells the story.
Drunk Elephant The Littles 8.0 brings Cucumis Melo Cantalupensis Fruit Extract, Dipotassium Glycyrrhizate, and Tocopherol as actives, while iOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles relies on Niacinamide, Tocopherol, and Tocopheryl Acetate. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Drunk Elephant The Littles 8.0 is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Cucumis Melo Cantalupensis Fruit Extract does the heavy lifting
IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Anyone who prefers clean, well-vetted formulations
Value comparison
Both sit in the premium bracket, so value comes down to formulation quality. Drunk Elephant The Littles 8.0 gets the nod here with its 9.8 overall score — you're getting more for a similar outlay.
Our verdict
Drunk Elephant The Littles 8.0 edges ahead with a slightly stronger formulation, but IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles is still a solid pick.


Frequently asked questions
Which is better: Drunk Elephant The Littles 8.0 or IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles?
Based on ingredient analysis, Drunk Elephant The Littles 8.0 scores higher overall. See the full score breakdown above for details on each attribute.
Do Drunk Elephant The Littles 8.0 and IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Drunk Elephant The Littles 8.0 and IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.