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Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 8.9/9.8 vs Drunk Elephant Protini Polypeptide Cream at 8.5/9.8. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide wins for hydration.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead, winning 1 of 5 attributes.
Scores last verified: June 2026
26 unique
8 in common
31 unique
Where Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide really shines is hydration efficacy, scoring 9.4 compared to Drunk Elephant Protini Polypeptide Cream's 6.3. With Glycerin, Butylene Glycol, and Pentylene Glycol in its top ingredients, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. Drunk Elephant Protini Polypeptide Cream scores 9.8 here versus 7.7 for Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide. That difference comes down to how each formula is built — the ingredient list tells the story.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while drunk Elephant Protini Polypeptide Cream relies on Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-1. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Drunk Elephant Protini Polypeptide Cream is better if you have
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
Both sit in the premium bracket, so value comes down to formulation quality. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide gets the nod here with its 8.9 overall score — you're getting more for a similar outlay.
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide edges ahead with a slightly stronger formulation, but Drunk Elephant Protini Polypeptide Cream is still a solid pick.
Based on ingredient analysis, Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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