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Drunk Elephant Protini Polypeptide Cream scores 8.5/9.8 and IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles scores 8.4/9.8 — a near-tie where your skin type decides the winner.
These two are neck and neck — just 0.1 points apart.
Scores last verified: June 2026
30 unique
31 unique
These two moisturisers take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Hydration Efficacy is another area of separation. IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles scores 9.8 here versus 6.3 for Drunk Elephant Protini Polypeptide Cream. That difference comes down to how each formula is built — the ingredient list tells the story.
Drunk Elephant Protini Polypeptide Cream brings Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, and Palmitoyl Tripeptide-1 as actives, while iOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles relies on Niacinamide, Tocopherol, and Tocopheryl Acetate. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Drunk Elephant Protini Polypeptide Cream is better if you have
IOPE Expert Retinol RX™ 2% Reti-Jection Serum for Wrinkles is better if you have
Both sit in the premium bracket, so value comes down to formulation quality. Drunk Elephant Protini Polypeptide Cream gets the nod here with its 8.5 overall score — you're getting more for a similar outlay.
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.
Based on ingredient analysis, Drunk Elephant Protini Polypeptide Cream scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.