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Differin Restorative Night Moisturizer scores 8.2/9.8 and Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol scores 8.2/9.8 — a near-tie where your skin type decides the winner.
These two are neck and neck — just 0.0 points apart.
Scores last verified: June 2026
25 unique
6 in common
23 unique
These two moisturisers take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Hydration Efficacy is another area of separation. Differin Restorative Night Moisturizer scores 9.8 here versus 7.8 for Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol. That difference comes down to how each formula is built — the ingredient list tells the story.
Differin Restorative Night Moisturizer brings Tocopheryl Acetate, Niacinamide, and Caffeine as actives, while mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol relies on Retinol, Tocopherol, and Ceramide Np. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Differin Restorative Night Moisturizer is better if you have
Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol is better if you have
At budget pricing with a score of 8.2, Differin Restorative Night Moisturizer is a decent pick. Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol sits at the luxury level with a 8.2 score — the extra cost doesn't translate to better scores here.
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.
Based on ingredient analysis, Differin Restorative Night Moisturizer scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.