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Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum scores 9.0/9.8 vs Differin Restorative Night Moisturizer at 8.2/9.8. Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum wins for active ingredients.
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum edges ahead, winning 1 of 5 attributes.
Scores last verified: April 2026
21 unique
10 in common
32 unique
Where Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum really shines is active ingredient strength, scoring 7.8 compared to Differin Restorative Night Moisturizer's 3.3. Its formula features Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine in high positions, signalling meaningful concentrations.
Ingredient Transparency is another area of separation. Differin Restorative Night Moisturizer scores 8.8 here versus 8.5 for Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum. That difference comes down to how each formula is built — the ingredient list tells the story.
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum brings Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine as actives, while differin Restorative Night Moisturizer relies on Tocopheryl Acetate, Niacinamide, and Caffeine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Differin Restorative Night Moisturizer is better if you have
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum is better if you have
At budget pricing with a score of 8.2, Differin Restorative Night Moisturizer is a decent pick. Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum sits at the premium level with a 9.0 score — the higher investment pays off in formulation quality.
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum edges ahead with a slightly stronger formulation, but Differin Restorative Night Moisturizer is still a solid pick.
Based on ingredient analysis, Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.