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CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores 8.5/9.8 and O HUI Prime Advancer Ampoule Serum scores 8.3/9.8 — a near-tie where your skin type decides the winner.
These two are neck and neck — just 0.2 points apart.
Scores last verified: June 2026
40 unique
7 in common
16 unique
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Irritation Risk is another area of separation. CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores 9.5 here versus 7.6 for O HUI Prime Advancer Ampoule Serum. That difference comes down to how each formula is built — the ingredient list tells the story.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid brings Ascorbyl Glucoside, Tocopheryl Acetate, and Hypnea Musciformis (Algae) Extract as actives, while o HUI Prime Advancer Ampoule Serum relies on Niacinamide, Bifida Ferment Lysate, and Panax Ginseng Root Extract. Both approaches have merit, but the positioning and supporting ingredients make the difference.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid is better if you have
O HUI Prime Advancer Ampoule Serum is better if you have
Both sit in the luxury bracket, so value comes down to formulation quality. CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid gets the nod here with its 8.5 overall score — you're getting more for a similar outlay.
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.
Based on ingredient analysis, CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
Honest skincare intel. No jargon, no gatekeeping — just the ingredients decoded.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.