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CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores 8.9/9.8 vs Differin Restorative Night Moisturizer at 8.2/9.8. CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid wins for active ingredients.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid edges ahead, winning 1 of 5 attributes.
Scores last verified: June 2026
39 unique
8 in common
23 unique
Where CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid really shines is active ingredient strength, scoring 7.2 compared to Differin Restorative Night Moisturizer's 3.3. Its formula features Ascorbyl Glucoside, Tocopheryl Acetate, and Hypnea Musciformis (Algae) Extract in high positions, signalling meaningful concentrations.
Ingredient Transparency is another area of separation. Differin Restorative Night Moisturizer scores 8.8 here versus 8.5 for CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid. That difference comes down to how each formula is built — the ingredient list tells the story.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid brings Ascorbyl Glucoside, Tocopheryl Acetate, and Hypnea Musciformis (Algae) Extract as actives, while differin Restorative Night Moisturizer relies on Tocopheryl Acetate, Niacinamide, and Caffeine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid is better if you have
Differin Restorative Night Moisturizer is better if you have
At luxury pricing with a score of 8.9, CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid delivers strong value. Differin Restorative Night Moisturizer sits at the budget level with a 8.2 score — the extra cost doesn't translate to better scores here.
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid edges ahead with a slightly stronger formulation, but Differin Restorative Night Moisturizer is still a solid pick.
Based on ingredient analysis, CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.