Anua Niacinamide 10% + TXA 4% Serum vs Paula's Choice Clinical 1% Retinol Treatment
Anua Niacinamide 10% + TXA 4% Serum scores 8.9/9.8 and Paula's Choice Clinical 1% Retinol Treatment scores 8.7/9.8 — a near-tie where your skin type decides the winner.
Head to head
Niacinamide 10% + TXA 4% Serum

Clinical 1% Retinol Treatment
Score comparison
These two are neck and neck — just 0.2 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Paula's Choice WINSIrritation Risk
TIEActive Ingredient Strength
Anua WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
9% overlapOnly in Anua Niacinamide 10% + TXA 4% Serum
36 unique
Only in Paula's Choice Clinical 1% Retinol Treatment
43 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Hydration Efficacy is another area of separation. Paula's Choice Clinical 1% Retinol Treatment scores 9.8 here versus 8.6 for Anua Niacinamide 10% + TXA 4% Serum. That difference comes down to how each formula is built — the ingredient list tells the story.
Anua Niacinamide 10% + TXA 4% Serum brings Niacinamide, Tranexamic Acid, and Alpha-Arbutin as actives, while paula's Choice Clinical 1% Retinol Treatment relies on Retinol, Tetrahexyldecyl Ascorbate, and Palmitoyl Oligopeptide. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Anua Niacinamide 10% + TXA 4% Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Paula's Choice Clinical 1% Retinol Treatment is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Retinol does the heavy lifting
Value comparison
At budget pricing with a score of 8.9, Anua Niacinamide 10% + TXA 4% Serum delivers strong value. Paula's Choice Clinical 1% Retinol Treatment sits at the mid-range level with a 8.7 score — the extra cost doesn't translate to better scores here.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.

Frequently asked questions
Which is better: Anua Niacinamide 10% + TXA 4% Serum or Paula's Choice Clinical 1% Retinol Treatment?
Based on ingredient analysis, Anua Niacinamide 10% + TXA 4% Serum scores higher overall. See the full score breakdown above for details on each attribute.
Do Anua Niacinamide 10% + TXA 4% Serum and Paula's Choice Clinical 1% Retinol Treatment share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Anua Niacinamide 10% + TXA 4% Serum and Paula's Choice Clinical 1% Retinol Treatment?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.