Anua Niacinamide 10% + TXA 4% Serum vs Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel
Anua Niacinamide 10% + TXA 4% Serum scores 8.9/9.8 and Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel scores 8.8/9.8 — a near-tie where your skin type decides the winner.
Head to head
Niacinamide 10% + TXA 4% Serum

Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel
Score comparison
These two are neck and neck — just 0.1 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Anua WINSIrritation Risk
Anua WINSActive Ingredient Strength
TIEIngredient Transparency
Anua WINSFormulation Safety
TIEIngredient face-off
11% overlapOnly in Anua Niacinamide 10% + TXA 4% Serum
34 unique
Shared ingredients
6 in common
Only in Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel
49 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Irritation Risk is another area of separation. Anua Niacinamide 10% + TXA 4% Serum scores 9.5 here versus 9.2 for Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel. That difference comes down to how each formula is built — the ingredient list tells the story.
Anua Niacinamide 10% + TXA 4% Serum brings Niacinamide, Tranexamic Acid, and Alpha-Arbutin as actives, while dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel relies on Hamamelis Virginiana (Witch Hazel) Water, Carnitine Hcl, and Gluconolactone. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
Anua Niacinamide 10% + TXA 4% Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Targeting specific concerns like aging or uneven tone — Hamamelis Virginiana (Witch Hazel) Water does the heavy lifting
Value comparison
Anua Niacinamide 10% + TXA 4% Serum comes in at budget pricing with a 8.9 score, which is solid value at that tier.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.

Frequently asked questions
Which is better: Anua Niacinamide 10% + TXA 4% Serum or Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel?
Based on ingredient analysis, Anua Niacinamide 10% + TXA 4% Serum scores higher overall. See the full score breakdown above for details on each attribute.
Do Anua Niacinamide 10% + TXA 4% Serum and Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between Anua Niacinamide 10% + TXA 4% Serum and Dr. Dennis Gross Skincare Alpha Beta® On The Spot Eliminator 2% Salicylic Acid Acne Treatment Gel?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.