AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic vs Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores 9.3/9.8 and Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol scores 9.1/9.8 — a near-tie where your skin type decides the winner.
Head to head
A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol
Score comparison
These two are neck and neck — just 0.2 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
AESTURA WINSIrritation Risk
TIEActive Ingredient Strength
Mother Science WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
20% overlapOnly in AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
24 unique
Only in Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol
23 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Active Ingredient Strength is another area of separation. Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol scores 6.4 here versus 6.1 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic brings Niacinamide, Gluconolactone, and Asiaticoside as actives, while mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol relies on Retinol, Tocopherol, and Ceramide Np. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Anyone who prefers clean, well-vetted formulations
Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Dimethyl Isosorbide
- Anyone who prefers clean, well-vetted formulations
Value comparison
At mid-range pricing with a score of 9.3, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic delivers strong value. Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol sits at the luxury level with a 9.1 score — the extra cost doesn't translate to better scores here.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.
Frequently asked questions
Which is better: AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic or Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol?
Based on ingredient analysis, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores higher overall. See the full score breakdown above for details on each attribute.
Do AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Mother Science Retinol Synergist Anti-Aging Treatment Serum with Malassezin + 0.3% Encapsulated Retinol?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.