AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic vs medicube Hyaluronic Multi Peptide PDRN Serum
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores 9.3/9.8 vs medicube Hyaluronic Multi Peptide PDRN Serum at 8.8/9.8. AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic wins for hydration.
Head to head

A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic

Hyaluronic Multi Peptide PDRN Serum
Score comparison
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead, winning 3 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
medicube WINSIrritation Risk
TIEActive Ingredient Strength
medicube WINSIngredient Transparency
medicube WINSFormulation Safety
TIEIngredient face-off
18% overlapOnly in AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
23 unique
Shared ingredients
7 in common
Only in medicube Hyaluronic Multi Peptide PDRN Serum
33 unique
Why AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic comes out ahead
Where AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic really shines is hydration efficacy, scoring 8.4 compared to medicube Hyaluronic Multi Peptide PDRN Serum's 9.8. With Glycerin, Butylene Glycol, and Dipropylene Glycol in its top ingredients, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. medicube Hyaluronic Multi Peptide PDRN Serum scores 7.5 here versus 6.1 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic brings Niacinamide, Gluconolactone, and Asiaticoside as actives, while medicube Hyaluronic Multi Peptide PDRN Serum relies on Niacinamide, Allantoin, and Adenosine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Anyone who prefers clean, well-vetted formulations
medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Propanediol
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic comes in at mid-range pricing with a 9.3 score, which is solid value at that tier.
Our verdict
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead with a slightly stronger formulation, but medicube Hyaluronic Multi Peptide PDRN Serum is still a solid pick.


Frequently asked questions
Which is better: AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic or medicube Hyaluronic Multi Peptide PDRN Serum?
Based on ingredient analysis, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores higher overall. See the full score breakdown above for details on each attribute.
Do AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and medicube Hyaluronic Multi Peptide PDRN Serum share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and medicube Hyaluronic Multi Peptide PDRN Serum?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.