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Medicube Hyaluronic Multi Peptide PDRN Serum scores 9.0/9.8 vs AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic at 8.3/9.8. Medicube Hyaluronic Multi Peptide PDRN Serum wins for hydration.
Medicube Hyaluronic Multi Peptide PDRN Serum edges ahead, winning 3 of 5 attributes.
Scores last verified: June 2026
23 unique
7 in common
33 unique
Where Medicube Hyaluronic Multi Peptide PDRN Serum really shines is hydration efficacy, scoring 9.8 compared to AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic's 8.4. With Propanediol, Glycerin, and Trehalose in its top ingredients, Medicube Hyaluronic Multi Peptide PDRN Serum delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. Medicube Hyaluronic Multi Peptide PDRN Serum scores 7.5 here versus 6.1 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
Medicube Hyaluronic Multi Peptide PDRN Serum brings Niacinamide, Allantoin, and Adenosine as actives, while aESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic relies on Niacinamide, Gluconolactone, and Asiaticoside. Both approaches have merit, but the positioning and supporting ingredients make the difference.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
Medicube Hyaluronic Multi Peptide PDRN Serum is better if you have
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic comes in at mid-range pricing with a 8.3 score, which is solid value at that tier.
Medicube Hyaluronic Multi Peptide PDRN Serum edges ahead with a slightly stronger formulation, but AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is still a solid pick.
Based on ingredient analysis, Medicube Hyaluronic Multi Peptide PDRN Serum scores higher overall. See the full score breakdown above for details on each attribute.
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.
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© 2026 Gracie. All rights reserved. Data sourced from Open Beauty Facts (ODbL) and EU CosIng.