AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic vs Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores 9.3/9.8 and Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.3/9.8 — a near-tie where your skin type decides the winner.
Head to head

A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic

Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
Score comparison
These two are neck and neck — just 0.0 points apart.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Kiehl's Since 1851 WINSIrritation Risk
TIEActive Ingredient Strength
Kiehl's Since 1851 WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
13% overlapOnly in AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
25 unique
Only in Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide
34 unique
Why these two are neck and neck
These two serums take different paths to a similar destination. Both formulas include solid hydrating ingredients, and the overall scores reflect that — the gap here is genuinely slim.
Hydration Efficacy is another area of separation. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide scores 9.4 here versus 8.4 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic brings Niacinamide, Gluconolactone, and Asiaticoside as actives, while kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide relies on Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Anyone who prefers clean, well-vetted formulations
Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
At mid-range pricing with a score of 9.3, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is a decent pick. Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide sits at the premium level with a 9.3 score — the extra cost doesn't translate to better scores here.
Our verdict
It's a close call — both products score within 0.3 points of each other. Your choice depends on your specific skin concerns.


Frequently asked questions
Which is better: AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic or Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide?
Based on ingredient analysis, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores higher overall. See the full score breakdown above for details on each attribute.
Do AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides & Peptide?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.