AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic vs Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores 9.3/9.8 vs Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum at 8.9/9.8. AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic wins for active ingredients.
Head to head

A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
Retinol Skin-Renewing Daily Micro-Dose Serum
Score comparison
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
Kiehl's WINSIrritation Risk
TIEActive Ingredient Strength
Kiehl's WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
12% overlapOnly in AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
25 unique
Only in Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum
37 unique
Why AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic comes out ahead
Where AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic really shines is active ingredient strength, scoring 6.1 compared to Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum's 7.8. Its formula features Niacinamide, Gluconolactone, and Asiaticoside in high positions, signalling meaningful concentrations.
Hydration Efficacy is another area of separation. Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum scores 9.6 here versus 8.4 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic brings Niacinamide, Gluconolactone, and Asiaticoside as actives, while kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum relies on Niacinamide, Acetyl Dipeptide-1 Cetyl Ester, and Adenosine. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Anyone who prefers clean, well-vetted formulations
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Targeting specific concerns like aging or uneven tone — Niacinamide does the heavy lifting
Value comparison
At mid-range pricing with a score of 9.3, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic delivers strong value. Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum sits at the premium level with a 8.9 score — the extra cost doesn't translate to better scores here.
Our verdict
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead with a slightly stronger formulation, but Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum is still a solid pick.

Frequently asked questions
Which is better: AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic or Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum?
Based on ingredient analysis, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores higher overall. See the full score breakdown above for details on each attribute.
Do AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.