AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic vs CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores 9.3/9.8 vs CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid at 8.5/9.8. AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic wins for hydration.
Head to head
A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid
Score comparison
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead, winning 2 of 5 attributes.
Scores last verified: July 2026
Attribute battle
Hydration Efficacy
CLINIQUE WINSIrritation Risk
TIEActive Ingredient Strength
CLINIQUE WINSIngredient Transparency
TIEFormulation Safety
TIEIngredient face-off
13% overlapOnly in AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic
24 unique
Only in CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid
41 unique
Why AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic comes out ahead
Where AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic really shines is hydration efficacy, scoring 8.4 compared to CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid's 9.8. With Glycerin, Butylene Glycol, and Dipropylene Glycol in its top ingredients, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic delivers stronger moisture-binding capability.
Active Ingredient Strength is another area of separation. CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid scores 7.2 here versus 6.1 for AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic. That difference comes down to how each formula is built — the ingredient list tells the story.
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic brings Niacinamide, Gluconolactone, and Asiaticoside as actives, while cLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid relies on Ascorbyl Glucoside, Tocopheryl Acetate, and Hypnea Musciformis (Algae) Extract. Both approaches have merit, but the positioning and supporting ingredients make the difference.
Best for your skin type
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Glycerin
- Anyone who prefers clean, well-vetted formulations
CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid is better if you have
- Sensitive skin — the low-irritation formula keeps things gentle
- Dry or dehydrated skin that craves moisture, thanks to Butylene Glycol
- Targeting specific concerns like aging or uneven tone — Ascorbyl Glucoside does the heavy lifting
Value comparison
At mid-range pricing with a score of 9.3, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic delivers strong value. CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid sits at the luxury level with a 8.5 score — the extra cost doesn't translate to better scores here.
Our verdict
AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic edges ahead with a slightly stronger formulation, but CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid is still a solid pick.
Frequently asked questions
Which is better: AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic or CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid?
Based on ingredient analysis, AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic scores higher overall. See the full score breakdown above for details on each attribute.
Do AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid share ingredients?
Yes, they share common ingredients. Check the ingredient face-off section above for a detailed comparison.
What's the main difference between AESTURA A-CICA365 Soothing Redness Relief Face Serum pH4.5 with Centella Asiatica + Hyaluronic and CLINIQUE Smart Clinical Repair™ Wrinkle Correcting Anti-Aging Serum with 1% Retinoid?
The key differences are in their active ingredients and formulation approach. Check the attribute battle above for a detailed breakdown.